Digital Cytogenetics at Krishna IVF: How IKAROS Supports Modern Chromosome Analysis Looking Beyond Hormones, Eggs and Sperm Infertility is usually caused by a combination of biological factors. Age, ovarian reserve, sperm production, reproductive anatomy, endocrine function and embryo development are all important. In some individuals and couples, however, an alteration in the number or structure […]
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World IVF Day 2026: What Patients Should Know Before Choosing Fertility Treatment Six considerations to support an informed decision By Prof. Dr. G.A. Rama Raju July 25 is World IVF Day, marking the birth of Louise Brown in 1978, the world’s first baby born through in vitro fertilisation. Since then, IVF has helped millions of
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Consanguineous Marriage and Genetic Risk: What Couples Should Know Before Pregnancy Marriage between relatives is a longstanding cultural and family tradition in several communities. Conversations about its medical implications should therefore remain respectful, factual and free from judgement. A consanguineous marriage does not mean that a couple will necessarily have a child with a genetic
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Y-Chromosome Microdeletion Testing Y-Chromosome Microdeletion Testing in Male Infertility: Why a Very Low Sperm Count Needs Deeper Evaluation A semen analysis is often the first test performed when a couple is finding it difficult to conceive. When the report shows an extremely low sperm concentration – or no sperm at all – it can be
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Standard G-Banded Karyotyping: Uses in Fertility and Pregnancy Standard G-Banded Karyotyping: What This Chromosome Test Can Reveal About Fertility and Pregnancy Chromosomes are organised packages of DNA found in nearly every cell of the body. Most people have 46 chromosomes arranged in 23 pairs. Changes in chromosome number or structure may be associated with infertility,
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Does the Uterus Have an Age Limit? New Research Suggests Yes – even with Donor Eggs Krishna IVF Clinic | Evidence-Based Fertility Care For many years, reproductive medicine has focused primarily on egg quality as the major determinant of IVF success. Donor egg IVF has transformed treatment for women with diminished ovarian reserve or menopause
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Why Waiting to Test the Male Partner is a Costly Fertility Mistake When a couple faces difficulty conceiving, a common but deeply flawed pattern often emerges: the female partner undergoes a battery of comprehensive tests, while the male partner’s evaluation is put on the back burner. Many couples think, “If her tests look normal, then
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Exploring the Future of IVF Through Medical Technology: My Visit to AMTZ, Visakhapatnam Prof. Dr. G. A. Rama Raju Today, I had the opportunity to visit the Andhra Pradesh MedTech Zone (AMTZ), Visakhapatnam, one of India’s most significant ecosystems for medical technology innovation. As someone deeply involved in reproductive medicine and assisted reproductive technology (ART),
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AI time-lapse embryo models now predict both clinical pregnancy and ploidy signals A 2026 Scientific Reports study developed spatiotemporal CNN models using time-lapse embryo videos plus maternal age. The pregnancy model reached an AUROC of 0.746 on external testing; the ploidy model reached an AUROC of 0.759 externally. This is clinically relevant because the model
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The New Standard of Hope: Inside the ASRM 2026 Guidelines for Fertility Preservationre A complex medical diagnosis—whether it involves cancer, the need for gonadotoxic therapy, or a high risk of premature ovarian insufficiency (POI)—is one of the most overwhelming challenges a person can face. In the midst of navigating treatments and survival, the dream of
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Understanding Your DNA: Why Chromosomal Health Matters in Reproductive Success By Dr G. A. Rama Raju, Director, Krishna IVF Clinic Introduction: The Blueprint of Life and Fertility Every successful pregnancy begins with a clear genetic plan – your DNA – organised into structures called chromosomes. Chromosomes are thread-like shapes made of DNA and proteins inside
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Infections and Fertility: The Silent Barrier to Parenthood By Dr. G. A. Rama Raju, MBBS, DNB, PhDDirector, Krishna IVF Clinic, Visakhapatnam Introduction While hormonal and genetic factors are commonly recognized causes of infertility, infections represent a significant and frequently overlooked contributor. A substantial proportion of global infertility cases are linked to infections, many of which
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