Effect of Stress on Female Infertility

The journey towards motherhood is often filled with a mix of emotions and challenges, particularly for women facing infertility issues. One factor that significantly impacts this journey is psychological stress. The realm of in vitro fertilization-embryo transfer (IVF-ET) is an intensive process, not just physically but also emotionally. Women undergoing IVF-ET frequently experience varying degrees of psychological distress, including symptoms of depression and anxiety. This blog delves into the intricate relationship between stress and female infertility, backed by recent studies and findings

The Psychological Network of IVF-ET

Recent research has shifted focus from just quantifying distress to understanding how symptoms like depression and anxiety interconnect in a network over time in women undergoing IVF-ET. This approach offers a nuanced view of psychological distress, recognizing that symptoms like ‘inability to control worry’, ‘sadness’, and ‘guilt’ can be central to a woman’s experience. Notably, ‘guilt’ emerges as a significant symptom, suggesting targeted psychological interventions could be beneficial.

Social Support as a Buffer

Another critical aspect in coping with infertility-related stress is the role of social support. A study involving 252 women undergoing infertility treatment highlighted the importance of partner, family, and friend support in mediating stress. The research demonstrated that different support contexts (partner, friend, and family) uniquely contribute to managing infertility stress. For instance, partner support showed a strong relationship with reduced relationship and sexual concerns, while family support played a broader role in alleviating stress across various domains.

Implications and Strategies

These insights underscore the necessity for comprehensive care approaches in fertility treatments, including psychological support. Health professionals need to recognize and address the complex emotional experiences of women undergoing infertility treatments. Encouraging positive support from social networks and focusing on coping skills training can be vital strategies. For instance, transforming active-avoidance coping into meaning-based and active-confronting strategies could be beneficial.


The journey through infertility and treatments like IVF-ET is multi-faceted, where psychological stress plays a significant role. Understanding the interconnectedness of symptoms and the value of social support can pave the way for more effective and compassionate care strategies. As we continue to explore this field, the focus should not only be on the physical aspects of infertility treatments but equally on the emotional and psychological wellbeing of women embarking on this challenging journey.


  1. Psychological Distress in IVF-ET Treatment : Psychological distress among women undergoing in vitro fertilization-embryo transfer: A cross-sectional and longitudinal network analysis. PubMed. 2023. Available from:
  2. The Role of Social Support in Coping with Infertility: Self-compassion mediates the relationship of perceived social support with life satisfaction in infertile women. National Center for Biotechnology Information (NCBI). Available from:
  3. Coping Strategies and Social Support: Anxiety, Difficulties, and Coping of Infertile Women. PubMed Central (PMC). Available from:
  4. Impact of Partner Support in Infertility Treatment: Supportive Social Interactions in Infertility Treatment Decrease Negative Emotions. National Center for Biotechnology Information (NCBI). Available from:
  5. Disclosure Strategies and Quality of Life: Disclosure strategies, social support, and quality of life in infertile women. PubMed. 2021. Available from:

Scroll to Top