Spindle View

Physicians and embryologists at the Krishna IVF Clinic can now observe and assess the majority of the egg’s spindle, enabling them to determine which eggs are most suitable for fertilization.

This technique also offers improved diagnosis of infertility in middle-aged women. This technology includes the use of an instrument called a LC polscope spindle view which offers a clear view of a critical but fragile structure within the eggs, known as a spindle.

The spindle’s job is to gather up, then tease apart the egg’s 23 chromosomes which carry genes bearing the code to life. If anything goes wrong with the spindle, chromosomes may not divide correctly, resulting in chromosomal abnormalities which may lead to a failure to conceive or miscarriages. As women age, the spindle in their eggs becomes less sturdy. Doctors have long understood the critical role of the spindle, but they have never before been able to observe it without destroying the eggs.

Traditionally, invitro fertilization has involved the transfer of multiple embryos. The result has been an increase in the number of triplets and even higher order multiples. This new instrument allows us to pick out and transfer only the healthiest embryos, resulting in fewer multiple births and decreasing the chances of damage to the spindle and chromosomes during an IVF procedure.

A guest lecture on the use spindle was delivered by Dr.Rama raju at Prague ESHRE in 2006 June

Spindle Images

Dr.Rama Raju delivering the lecture in PREGUE